结构=(信息)⇒功能
分化是基因差异表达的结果
THE CELL 第七章 gene control
早期认为细胞分化是DNA不断丢失,所以才有体细胞克隆实验,去证明体细胞中仍然有全部的基因组信息。
生物学 都是条件性的必然性。
Epigenetic landscaping: how chromatin is regulated to achieve proper gene expression during cell differentiation?
Gene regulation
- transcriptional control
- RNA-processing control
- RNA transport & localization control
- mRNA degradation control
- translational control
- protein degradation control